Structural basis of the SWI/SNF-bound transcription pre-initiation complex

ABSTRACT: DSSO crosslinking of SwiSnf + Mediator + Pre-initiation Complex. Two replicate experiments starting with 300 ug of protein and 6 mM DSSO. Crosslinked peptides were fractionated by size-exclusion chromatography (SEC) and 8 SEC were analyzed by LC-MS on an Orbitrap Exploris 480 instrument. The first set of 8 fractions was run in technical replicate, once with a FAIMS source and once without.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)

SUBMITTER: Roger Kornberg  

PROVIDER: MSV000097892 | MassIVE | Wed May 14 14:44:00 BST 2025

SECONDARY ACCESSION(S): PXD063937

REPOSITORIES: MassIVE