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Multi-omics analysis reveals maternal gut microbiota-derived short-chain fatty acids and progesterone are associated with offspring birth weight in sows

ABSTRACT:

Piglet birth weight is a key determinant of preweaning survival and subsequent growth performance, yet the role of maternal gut microbiota in relation to offspring birth weight in sows remains incompletely characterized. This study aimed to investigate the association between maternal gut microbiota and offspring birth weight in sows. Fecal samples were collected from 260 Landrace × Yorkshire (LY) sows at gestation day 100, and sows were categorized into high birth weight (HBW; 1.41 ± 0.02 kg, 16.25 ± 0.25 piglets/litter, n = 59) and low birth weight (LBW; 1.07 ± 0.02 kg, 12.19 ± 0.22 piglets/litter, n = 52) groups based on the average birth weight of live-born piglets and live litter size. Fecal untargeted metabolomics was performed between groups.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

PROVIDER: MTBLS13791 | MetaboLights | 2026-02-22

REPOSITORIES: MetaboLights

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			Action	DRS
	NEG_Hl16XXJ_H1071.raw	Raw
	NEG_Hl16XXJ_H1082.raw	Raw
	NEG_Hl16XXJ_H1141.raw	Raw
	NEG_Hl16XXJ_H1144.raw	Raw
	NEG_Hl16XXJ_H1146.raw	Raw

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