Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA321855
TISSUE(S): Hela Cells
SUBMITTER: Zhaoyuan,Fang
REPOSITORIES: NODE
eLife 20160325
Progression through the mitotic cell cycle requires periodic regulation of gene function at the levels of transcription, translation, protein-protein interactions, post-translational modification and degradation. However, the role of alternative splicing (AS) in the temporal control of cell cycle is not well understood. By sequencing the human transcriptome through two continuous cell cycles, we identify ~1300 genes with cell cycle-dependent AS changes. These genes are significantly enriched in ...[more]