Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Gene expression data of BBB and BCB two-cell embryos

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA120069 | ENA |

REPOSITORIES: ENA

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Publications

Early transcription from the maternal genome controlling blastomere integrity in mouse two-cell-stage embryos.

Han Zhiming Z   Mtango Namdori R NR   Zhong Zhisheng Z   Vassena Rita R   Latham Keith E KE  

American journal of physiology. Cell physiology 20100127 5


Blastomere cytofragmentation in mammalian embryos poses a significant problem in applied and clinical embryology. Mouse two-cell-stage embryos display strain-dependent differences in the rate of cytofragmentation, with a high rate observed in C3H/HeJ embryos and a lower rate observed in C57BL/6 embryos. The maternally inherited genome exerts the strongest effect on the process, with lesser effects mediated by the paternally inherited genome and the ooplasm. The effect of the maternal genome is t  ...[more]

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