Genomics,Multiomics

Dataset Information

0

Mus musculus


ABSTRACT: Sex-related differences in gene expression following Coxiella burnetii infection: potential role of circadian rhythm

OTHER RELATED OMICS DATASETS IN: E-GEOD-21065

PROVIDER: PRJNA126755 | ENA |

REPOSITORIES: ENA

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Publications

Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm.

Textoris Julien J   Ban Leang Heng LH   Capo Christian C   Raoult Didier D   Leone Marc M   Mege Jean-Louis JL  

PloS one 20100813 8


<h4>Background</h4>Q fever, a zoonosis due to Coxiella burnetii infection, exhibits sexual dimorphism; men are affected more frequently and severely than women for a given exposure. Here we explore whether the severity of C. burnetii infection in mice is related to differences in male and female gene expression profiles.<h4>Methodology/principal findings</h4>Mice were infected with C. burnetii for 24 hours, and gene expression was measured in liver cells using microarrays. Multiclass analysis id  ...[more]

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