Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: DNA methylation in normal PC, MGUS, SMM and MM

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA187924 | ENA |

REPOSITORIES: ENA

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Publications


Epigenetic changes play important roles in carcinogenesis and influence initial steps in neoplastic transformation by altering genome stability and regulating gene expression. To characterize epigenomic changes during the transformation of normal plasma cells to myeloma, we modified the HpaII tiny fragment enrichment by ligation-mediated PCR assay to work with small numbers of purified primary marrow plasma cells. The nano-HpaII tiny fragment enrichment by ligation-mediated PCR assay was used to  ...[more]

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