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Expression profiling from mouse embryonic stem cells (ESCs)

ABSTRACT: Expression profiling from mouse embryonic stem cells (ESCs)

PROVIDER: PRJNA412002 | ENA |

REPOSITORIES: ENA

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Metabolomics Workbench ST000003 - GNPS - Metabolomic analysis of mouse embryonic fibroblasts, embryonic stem cells, and induced pluripotent stem cells

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AP-MS of EPOP in mouse embryonic stem cells

Project description:A Flag-tagged version of murine EPOP was expressed in mouse embryonic stem cells (ESCs) at near to endogenous levels and purified using an anti-FLAG affinity matrix.

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Effect of L-Proline on mouse embryonic stem cells (ESCs)

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Expression profiling from mouse embryonic stem cells (ESCs)

Project description:Sin3a, a known master scaffold, provides unique contact surfaces for interaction with particular accessory proteins to repress the transcription of specific genes. Surprisingly, our results also suggest that Sin3a has a role in transcriptional activation. We compared gene expression differences between Sin3a knockdown and control ESCs with mouse gene expression microarrays and identified an approximately equal distribution of up- and down-regulated genes following Sin3a knockdown in mouse ESCs. We propose that Sin3a collaborates with Tet1 to demethylate adjacent genomic regions and, ultimately, facilitates actively transcribed gene expression in mouse ESCs.

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Effect of L-Proline on mouse embryonic stem cells (ESCs)

2013-09-05 | GSE50603 | GEO

Effect of L-Proline on mouse embryonic stem cells (ESCs)

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MS-based quantitative proteomic analysis of embryonic stem cells with normal and reduced expression of Rsl24d1.

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