Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Change in cellular mRNA expression caused by US7 or US8

ABSTRACT: Change in cellular mRNA expression caused by US7 or US8

PROVIDER: PRJNA563838 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

mRNA expression of B7 family molecules in blood of patients with colorectal cancer

Project description:Primary outcome(s): Relationship with mRNA expression of B7 family molecules in blood of patients with colorectal cancer and clinicopathological factors

| 2623816 | ecrin-mdr-crc

Change in cellular mRNA expression caused by US7 or US8

Project description:HCMV glycoproteins US7 and US8 target the innate immune response. We used microarrays to detail the global programme of gene expression and identified to down-regulated genes by US7 or US8.

2019-09-05 | GSE136835 | GEO

High-throughput sequencing reveals change of microRNA expression caused by allopolyploidization in Cucumis

Project description:High-throughput sequencing reveals change of microRNA expression caused by allopolyploidization in Cucumis

| PRJNA316943 | ENA

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

Project description:Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

| PRJNA661432 | ENA

Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

Project description:Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

| PRJNA527649 | ENA

The change of mRNA stability upon T cell activation

Project description:The change of mRNA stability upon T cell activation

| PRJNA453797 | ENA

The change of mRNA expression in murine immortalized podocyte after miR-26a silencing

Project description:The change of mRNA expression in murine immortalized podocyte were analyzed after miR-26a silencing. These results provide a basical information of molecular pathology in podocyte biology.

2014-10-01 | GSE51210 | GEO

Change in gene expression of a canine melanoma cell line caused by exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) .

Project description:Nonsteroidal anti-inflammatory drugs (NSAIDs) has been suggested as adjunctive anti-tumor agents in human and veterinary medicine. However, its anti-tumor molecular machinery is still controversial. Therefore, we performed whole transcriptome analysis to discover gene expression influenced by NSAIDs treatment. A canine melanoma cell line (Mi/CMM1) was treated by three NSAIDs, piroxicam, carprofen, and robenacoxib, at their half maximal (50%) inhibitory concentrations (116 ÂµM, 779 ÂµM, and 156 ÂµM) for 6 hours. Subsequently, total RNA were extracted and microarray analysis was performed to evaluate change in gene expression caused by NSAIDs treatment. Each condition had three biological replicates.

2016-03-09 | E-GEOD-78988 | biostudies-arrayexpress

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

Project description:Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

| PRJNA515481 | ENA

Splicing factor PRPF31 retinitis pigmentosa (RP11) is caused by disrupted alternative splicing programmes for genes implicated in pre-mRNA splicing, cellular adhesion and ciliogenesis

Project description:Mutations in pre-mRNA processing factors (PRPFs) cause autosomal dominant retinitis pigmentosa (RP), but it is unclear why mutations in ubiquitously expressed genes cause retinal disease. We have generated transcriptome profiles from RP11 (PRPF31-mutated) patient-derived retinal organoids and retinal pigment epithelium (RPE), as well as Prpf31+/- mouse tissues, which revealed that disrupted alternative splicing occurred for specific splicing programmes. Mis-splicing of genes encoding pre-mRNA splicing proteins was limited to patient-specific retinal cells and Prpf31+/- mouse retinae and RPE. Mis-splicing of genes implicated in ciliogenesis and cellular adhesion was associated with severe RPE defects that include disrupted apical-basal polarity, reduced trans-epithelial resistance and phagocytic capacity, and decreased cilia length and incidence. Disrupted cilia morphology also occurred in patient-derived photoreceptors, associated with progressive degeneration and cellular stress. In situ gene-editing of a pathogenic mutation rescued protein expression and key cellular phenotypes in RPE and photoreceptors, providing proof-of-concept for future therapeutic strategies.

2018-08-20 | PXD010821 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data