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RNA-seq Analysis of control and CyPA-stimulated BEAs-2B cells Transcriptomes

ABSTRACT: RNA-seq Analysis of control and CyPA-stimulated BEAs-2B cells Transcriptomes

PROVIDER: PRJNA704573 | ENA |

REPOSITORIES: ENA

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RNA-seq Analysis of control and CyPA-stimulated BEAs-2B cells Transcriptomes

Project description:Purpose: The goals of this study are to compare the difference between control and CyPA-stimulated BEAs-2B cells Transcriptomes Methods: After receiving anesthesia with pentobarbital sodium, each mouse of the WT group, hCD147 group, and hACE2 group was infected with SARS-CoV-2 by nasal drip at a dose of 3 × 105 TCID50. The lung tissues were take for RNA-seq at 2 dpi. Results: CyPA-stimulated BEAs-2B cells showed upregulated expression of a variety of proinflammatory cytokines and chemokines, including IL6, IL1b, MCP-1, CXCL1 and CXCL2, as well as several AP-1 family members, including c-FOS, FOSL1 and FOSL2 that promote the transcription of multiple cytokine genes during inflammation Conclusions: CyPA induces cytokine expression through the CD147-mediated MAPK pathway

2021-09-29 | GSE167402 | GEO

high-throughput sequencing of circRNAs in T-BEAS-2B cells and C-BEAS-2B cells

Project description:We report the differential expression of circRNAs between T-BEAS-2B cells (cadmium-transformed BEAS-2B cells) and C-BEAS-2B cells (passage-matched control BEAS-2B cells) by high-throughput sequencing. T-BEAS-2B cells are BEAS-2B cells transformed by cadmium at 2.0 μM for twenty weeks, and C-BEAS-2B cells are their passage-matched control. RNAs were sequenced on Illumina HiSeq Xten platform in triplicates, and expressions of circRNAs were calculated by TPM (transcripts per kilobase of exon model per million mapped reads). Clean data per sample exceeds 10 GB. We find 235 significantly up-regulated circRNAs and 271 significantly down-regulated circRNAs in T-BEAS-2B cells relative to C-BEAS-2B cells. Our work provides clues and evidence for exploring the mechanism of circRNAs in cadmium carcinogenesis.

2024-01-26 | GSE165549 | GEO

BEAS-2B cells: Control versus chemical exposure

Project description:Transcriptonal profiling of BEAS-2B cells: Control versus skin sensitizers; Control versus respiratory sensitizers; Control versus non-sensitizing irritants

2013-12-01 | GSE44729 | GEO

BEAS-2B cells: Control versus chemical exposure

Project description:Transcriptonal profiling of BEAS-2B cells: Control versus skin sensitizers; Control versus respiratory sensitizers; Control versus non-sensitizing irritants Replicates: 3 biological replicates; Exposure: 10 different chemicals versus solvent, 1 exposure concentration (IC20); Exposure time: 3 different exposure time points;

2013-12-01 | E-GEOD-44729 | biostudies-arrayexpress

Proteome analysis of Beas-2B cells with S. pneumoniae D39

Project description:Proteome analysis of Beas-2B cells with S. pneumoniae D39 after 9 h and 16 h of infection

2023-07-04 | PXD039059 | Pride

HmiOA4.1 microarrays-BEAS-2B cells treatment with NiCl2

Project description:To investigate the effects of nickel on miRNAs expression in BEAS-2B cells.

2018-04-17 | GSE67997 | GEO

Silica-exposed BEAS-2B epithelial cells

Project description:We used mass spectrometry to profile changes in metabolites, proteins, and phosphorylation in silica-exposed BEAS-2B epithelial cells.

2022-07-28 | PXD035608 | iProX

Comparison of gene expression profiles in chromate transformed BEAS-2B cells

Project description:We established chromate transformed cell lines by chronic exposure of normal human bronchial epithelial BEAS-2B cells to low doses of hexavalent chromium followed by anchorage-independent growth. The gene expression profiles were analyzed in the established cell lines. The gene expression profiles from six chromate transformed cell lines were remarkably similar to each other yet differed significantly from that of either control cell line or normal Beas-2B cells. A total of 409 differentially expressed genes were identified in chromate transformed cells compared to control cells.

2010-09-14 | GSE24025 | GEO

RNA-seq to investigate effect miRNA 210 knockdown of airway respiratory muscle cells treated with BEAS-2B cell condition media

Project description:Airway smooth muscle cells were stimulated with conditioned medium from BEAS-2B cells in the absence (Control) or Inhibition of miR-210.

2020-06-18 | E-MTAB-9224 | biostudies-arrayexpress

Next Generation Sequencing identifies differentially expressed genes regulated by PM2.5 exposure in BEAS-2B cells [RNA-seq]

Project description:We report the application of RNA-sequencing for high-throughput profiling of transcriptomes in BEAS-2B cells after exposure to PM2.5 for 24 hours..

2022-07-27 | GSE182199 | GEO

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