Endogenous S-nitrosoproteome in colorectal cancer patients
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q-Tof Premier
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Yi-Ju Chen
PROVIDER: PXD000467 | Pride | 2014-08-20
REPOSITORIES: Pride
Publications
Decoding the s-nitrosoproteomic atlas in individualized human colorectal cancer tissues using a label-free quantitation strategy.
Chen Yi-Ju YJ Ching Wei-Chieh WC Chen Jinn-Shiun JS Lee Tzong-Yi TY Lu Cheng-Tsung CT Chou Hsiao-Chiao HC Lin Pei-Yi PY Khoo Kay-Hooi KH Chen Jenn-Han JH Chen Yu-Ju YJ
Journal of proteome research 20140804 11
The abnormal S-nitrosylation induced by the overexpression and activation of inducible nitric oxide synthase (iNOS) modulates many human diseases, such as inflammation and cancer. To delineate the pathophysiological S-nitrosoproteome in cancer patients, we report an individualized S-nitrosoproteomic strategy with a label-free method for the site-specific quantification of S-nitrosylation in paired tumor and adjacent normal tissues from 11 patients with colorectal cancer (CRC). This study provide ...[more]
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