Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Muscle Cell
DISEASE(S): Peripheral Primitive Neuroectodermal Tumor
SUBMITTER: Kristina Bennet Emdal
LAB HEAD: Jesper Velgaard Olsen
PROVIDER: PXD002765 | Pride | 2017-04-19
REPOSITORIES: Pride
Radic-Sarikas Branka B Tsafou Kalliopi P KP Emdal Kristina B KB Papamarkou Theodore T Huber Kilian V M KV Mutz Cornelia C Toretsky Jeffrey A JA Bennett Keiryn L KL Olsen Jesper V JV Brunak Søren S Kovar Heinrich H Superti-Furga Giulio G
Molecular cancer therapeutics 20161115 1
Improvements in survival for Ewing sarcoma pediatric and adolescent patients have been modest over the past 20 years. Combinations of anticancer agents endure as an option to overcome resistance to single treatments caused by compensatory pathways. Moreover, combinations are thought to lessen any associated adverse side effects through reduced dosing, which is particularly important in childhood tumors. Using a parallel phenotypic combinatorial screening approach of cells derived from three pedi ...[more]