Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Pluripotent Stem Cell, Granulosa Cell, Fibroblast
SUBMITTER: Putty-Reddy Sudhir
LAB HEAD: Prof. Chung-Hsuan Chen
PROVIDER: PXD004366 | Pride | 2016-12-23
REPOSITORIES: Pride
Sudhir Putty-Reddy PR Kumari Madireddy Pavana MP Hsu Wei-Ting WT Chen Chein-Hung CH Kuo Hung-Chih HC Chen Chung-Hsuan CH
Scientific reports 20161103
Molecular-level differences ranging from genomes to proteomes, but not N-glycoproteomes, between human induced pluripotent stem cells (hiPSCs) and embryonic stem cells (hESCs) have been assessed to gain insights into cell reprogramming and induced pluripotency. Our multiplexed quantitative N-glycoproteomics study identified altered N-glycoproteins that significantly regulate cell adhesion processes in hiPSCs compared to hESCs. The integrative proteomics and functional network analyses of the alt ...[more]