Proteomics

Dataset Information

53

Lipases from Metagenomic Sources


ABSTRACT: Functional Metaproteomic approach was used to discover lipolytic enzymes.

INSTRUMENT(S): Synapt MS

ORGANISM(S): soil metagenome  

TISSUE(S): Tissue Not Applicable To Dataset

DISEASE(S): Not Available

SUBMITTER: Premankur Sukul  

LAB HEAD: Prof. Dr. Lars I. Leichert

PROVIDER: PXD005148 | Pride | 2017-03-09

REPOSITORIES: pride

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Publications

Simple discovery of bacterial biocatalysts from environmental samples through functional metaproteomics.

Sukul Premankur P   Schäkermann Sina S   Bandow Julia E JE   Kusnezowa Anna A   Nowrousian Minou M   Leichert Lars I LI  

Microbiome 20170303 1


Bacterial biocatalysts play a key role in our transition to a bio-based, post-petroleum economy. However, the discovery of new biocatalysts is currently limited by our ability to analyze genomic information and our capacity of functionally screening for desired activities. Here, we present a simple workflow that combines functional metaproteomics and metagenomics, which facilitates the unmediated and direct discovery of biocatalysts in environmental samples. To identify the entirety of lipolytic  ...[more]

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