Proteomics

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Proteomic response of Bacillus subtilis 3610 to nanoparticles exposition


ABSTRACT: The natural biotope of Bacillus subtilis is the upper layer of soil where it grows as a biofilm. To mimic this physiological development and study the impact of nanoparticles during the formation of a biofilm in a contaminated soil, we have studied the proteomic response of the ancestral strain Bacillus subtilis 3610, which is able to form biofilm contrary to the 168 laboratory strain. The bacteria were grown on soft agar plates containing n-ZnO, n-TiO2 or ZnSO4 metal ion.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Bacillus Subtilis

SUBMITTER: Thierry Rabilloud  

LAB HEAD: Rabilloud

PROVIDER: PXD006444 | Pride | 2018-10-24

REPOSITORIES: Pride

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Publications

Impact of nanoparticles on the Bacillus subtilis (3610) competence.

Eymard-Vernain Elise E   Luche Sylvie S   Rabilloud Thierry T   Lelong Cécile C  

Scientific reports 20180214 1


Due to the physicochemical properties of nanoparticles, the use of nanomaterials increases every year in industrial and medical processes. At the same time, the increasing number of bacteria becoming resistant to many antibiotics, mostly by a horizontal gene transfer process, is a major public health concern. We herein report, for the first time, the role of nanoparticles in the physiological induction of horizontal gene transfer in bacteria. Besides the most well-known impacts of nanoparticles  ...[more]

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