Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Cell Culture
SUBMITTER: Gereon Poschmann
LAB HEAD: Gereon Poschmann
PROVIDER: PXD006457 | Pride | 2019-02-19
REPOSITORIES: Pride
Werthebach Michael M Stewart Fiona A FA Gahlen Alisa A Mettler-Altmann Tabea T Akhtar Irfan I Maas-Enriquez Kerstin K Droste Andrea A Eichmann Thomas O TO Poschmann Gereon G Stühler Kai K Beller Mathias M
Cell reports 20190301 13
Lipid droplets (LDs) are the universal cellular storage organelles for esterified neutral lipids. The increasing number of characterized LD-associated proteins attained LDs with hitherto unexpected functions on top of their classical role as energy depot. Here, we characterize the LD-associated protein CG9186 of Drosophila by a CRISPR/Cas9-derived mutant fly line. While the mutant flies only showed a mild triacylglycerol storage phenotype, they were highly protected from desiccation stress, like ...[more]