The Study of ATRA-Induced Differentiation of the HL-60 Cell Line

ABSTRACT: Shotgun mass-spectrometric experiment was performed with HL-60 cells induced to differentiation at 0, 3, 24, 48 and 96h after ATRA treatment. Obtained data has been used for label-free quantification by SPIRE platform based on spectral count. Results on proteome profiling were used for up-stream regulator search in geneXplain platform (http://genexplain.com/).

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Cell Suspension Culture

DISEASE(S): Acute Leukemia

SUBMITTER: Svetlana Novikova  

LAB HEAD: Victor Zgoda

PROVIDER: PXD006768 | Pride | 2021-09-07

REPOSITORIES: Pride