Proteomics,Multiomics

Dataset Information

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Centruroides henzti venom - Venom-gland transcriptomics and venom proteomics of the Hentz striped scorpion (Centruroides hentzi; Buthidae) reveal high toxin diversity in a harmless member of a lethal family


ABSTRACT: Venom proteomics for the scorpion Centruroides hentzi

OTHER RELATED OMICS DATASETS IN: PRJNA340270

INSTRUMENT(S): Q Exactive

ORGANISM(S): Centruroides Hentzi

TISSUE(S): Venom Gland

SUBMITTER: Darin Rokyta  

LAB HEAD: Darin Rene Rokyta

PROVIDER: PXD007788 | Pride | 2017-12-19

REPOSITORIES: Pride

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Publications

Venom-gland transcriptomics and venom proteomics of the Hentz striped scorpion (Centruroides hentzi; Buthidae) reveal high toxin diversity in a harmless member of a lethal family.

Ward Micaiah J MJ   Ellsworth Schyler A SA   Rokyta Darin R DR  

Toxicon : official journal of the International Society on Toxinology 20171214


Of the 14 extant scorpion families, Buthidae has the most thoroughly characterized venoms. Most of this characterization, however, has been limited to species with medically significant stings, including members of the Centruroides genus, which have caused human deaths (e.g., Centruroides sculpturatus). To understand the origin and evolution of highly toxic venoms, we should also characterize the more harmless venoms of close relatives. We used Illumina sequencing to separately characterize the  ...[more]

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