Proteomics

Dataset Information

0

Exoproteomes of S. aureus spa type t437 isolates


ABSTRACT: A total of 20 S. aureus spa type t437 isolates were used for exoproteome analyses in the present study. Ten of them were selected from MLVA type (MT) 621 group which has was shown to represent the most predominant class of S. aureus isolates with the spa type t437; the other ten isolates belonged to different MTs, namely MT1870, MT4125, MT1035, MT1297, MT2075, MT1875, MT2322, MT1831, MT4183 and MT1830.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Staphylococcus Aureus

SUBMITTER: Andreas Otto  

LAB HEAD: Doerte Becher

PROVIDER: PXD009082 | Pride | 2019-05-24

REPOSITORIES: Pride

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Publications

Exoproteome Heterogeneity among Closely Related Staphylococcus aureus t437 Isolates and Possible Implications for Virulence.

Zhao Xin X   Palma Medina Laura M LM   Stobernack Tim T   Glasner Corinna C   de Jong Anne A   Utari Putri P   Setroikromo Rita R   Quax Wim J WJ   Otto Andreas A   Becher Dörte D   Buist Girbe G   van Dijl Jan Maarten JM  

Journal of proteome research 20190605 7


Staphylococcus aureus with spa-type t437 has been identified as a predominant community-associated methicillin-resistant S. aureus clone from Asia, which is also encountered in Europe. Molecular typing has previously shown that t437 isolates are highly similar regardless of geographical regions or host environments. The present study was aimed at assessing to what extent this high similarity is actually reflected in the production of secreted virulence factors. We therefore profiled the extracel  ...[more]

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