Ontology highlight
ABSTRACT:
INSTRUMENT(S): impact II
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Testis, Brain, Liver, Retina, Kidney
SUBMITTER: Jenny Moon
LAB HEAD: Robert S. Molday
PROVIDER: PXD009143 | Pride | 2018-07-20
REPOSITORIES: Pride
Scientific reports 20180717 1
P4-ATPases are a subfamily of P-type ATPases that flip phospholipids across membranes to generate lipid asymmetry, a property vital to many cellular processes. Mutations in several P4-ATPases have been linked to severe neurodegenerative and metabolic disorders. Most P4-ATPases associate with one of three accessory subunit isoforms known as CDC50A (TMEM30A), CDC50B (TMEM30B), and CDC50C (TMEM30C). To identify P4-ATPases that associate with CDC50A, in vivo, and determine their tissue distribution, ...[more]