Signaling Mechanisms in Initiation of Lithium-Induced Nephrogenic Diabetes Insipidus

ABSTRACT: Lithium treatment is commonly used to treat bipolar disorder. However, this treatment disrupts kidney fuctionality. We used microdissected cortical collecting ducts to study proteomics and ultimately discover what changes occur in protein expression after 72-hr lithium treatment.

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Epithelial Cell, Kidney

DISEASE(S): Nephrogenic Diabetes Insipidus

SUBMITTER: Gabirelle Gilmer  

LAB HEAD: Mark Knepper

PROVIDER: PXD010118 | Pride | 2019-07-01

REPOSITORIES: Pride