Characterization of human plasma depletome from patients with schizophrenia

ABSTRACT: The proteome of blood plasma is an interesting source of biomarkers and a potential way to improve treatment outcomes in psychiatric disorders. But its wide dynamic concentration range makes reducing its complexity necessary. Thus, in proteomic studies, a few of the most abundant proteins are depleted and normally discarded. This high-abundance fraction, called the depletome, however, is a source of potential biomarkers due to nonspecific bindings with low abundance proteins. In this work, we characterized the high-abundance fraction from schizophrenia patients using a shotgun mass spectrometry approach.

OTHER RELATED OMICS DATASETS IN: MODEL1109130000 MODEL1909260003 MODEL1909260004 MODEL1703310000 MODEL1909260005 MODEL1909260006 MODEL1311110000 MODEL1311110001

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

SUBMITTER: Licia C. Silva-Costa  

LAB HEAD: Daniel Martins-de-Souza

PROVIDER: PXD010273 | Pride | 2019-10-23

REPOSITORIES: Pride