Puniya2021 - Naive CD4+ T cell metabolic model

ABSTRACT: CD4+ T cells are critical components in the human immune system. They produce cytokines to fight against pathogens and abnormal cells and stimulate other cells, such as B cells, macrophages, and neutrophils, to generate an immune response. Naive CD4+ T cells are precursor cells that can differentiate into T helper - 1, - 2, - 17 (Th1, Th2, Th17) and regulatory T cells (Tregs) subtypes based on the type of pathogens or disease. The naive CD4+ T cell model consists of 5179 reactions, 3153 metabolites, and 1055 genes. Together with Th1, Th2, and Th17 models, the naive CD4+ T cell model helped identify drug targets and repurposable drugs against autoimmune diseases.

OTHER RELATED OMICS DATASETS IN: E-PROT-3 MSV000079514 E-PROT-1 PXD001491 PXD019293 PXD014201 PXD022287 PXD018993 PXD015517 PXD023738 PXD020227 PXD010185 PXD013300 PXD024162 PXD016171 PXD010969 PXD010439 PXD002869 PXD009741 PXD007038 PXD013767 PXD007174 PXD013150 PXD022471 PXD012688 PXD022772 PXD007700 PXD015511 PXD009595 PXD004449 PXD015394 PXD010288 PXD010292 PXD009448 PXD006344 PXD016989 PXD023038 PXD019858 PXD019690 PXD004184 PXD005896 PXD012865 PXD015558 PXD013667 PXD019202 PXD012969 PXD021899 PXD014159 PXD013369 PXD011411 PXD012503 PXD022599 PXD001576 PXD013061 PXD014307 PXD011879 PXD019787 PXD024339 PXD003704 PXD012923 PXD002468 PXD019791 PXD007943 PXD005028 PXD003755 PXD014844 PXD016042 PXD009955 PXD007922 PXD020756 PXD013704 PXD013282 PXD017083 PXD014000 PXD014556 PXD010153 PXD015438 PXD021756 PXD015756 PXD013264 PXD014358 PXD025237 PXD006179 PXD010588 PXD013280 PXD013083 PXD002160 PXD014573 PXD008954 PXD011616 PXD024242 PXD016192 PXD009275 PXD006262 PXD008808 PXD012189 PXD009823 PXD016455

SUBMITTER: Bhanwar Lal Puniya  

PROVIDER: MODEL1909260003 | BioModels | 2023-11-27

REPOSITORIES: BioModels