Quantitative proteomics of TGFβ1-stimulated endothelial cells using iTRAQ, LC-MSMS
ABSTRACT: Endothelial to mesenchymal transition is a possible source of myofibroblasts, which play a crucial role in the pathogenesis of fibrosis. EndMT participate in tissue fibrotic processes in various organs. TGF-β family growth factors are involved in the initiation of EndMT. This process plays a crucial role n the pathogenesis of various fibrotic diseases.