Quantitative Proteomics analysis of LX-2 Responses to Irradiation and TGF-β1 Description

ABSTRACT: The human hepatic stellate cell line LX2 was treated with 8 Gy X-ray irradiation and/or 2ng/ml recombinant human TGF-β1. The iTRAQ-based high throughput quantitative proteomic approach was used to obtain a comprehensive view of the protein ensembles affected by irradiation and/or TGF-β1 treatment on LX2. This study provides clues for further investigation of the mechanisms behind radiation-induced liver fibrosis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatic Stellate Cell

SUBMITTER: Baoying Yuan  

LAB HEAD: Zhaochong Zeng

PROVIDER: PXD011242 | Pride | 2018-12-04

REPOSITORIES: Pride