Protein complexes between PGRMC1 and actin-associated proteins are disrupted by AG-205

ABSTRACT: PGRMC1 is a protein from the MAPR family with a range of cellular functions. PGRMC1 has been described to play a role in regulating membrane trafficking and in cancer progression and response to therapies. To further understand the functions of PGRMC1 and the mechanism of the small molecule inhibitor of PGRMC1, AG-205, proteins differentially bound to PGRMC1 were identified following AG-205 treatment of MIA PaCa-2 cells.

OTHER RELATED OMICS DATASETS IN: MODEL1109130000 MODEL1909260003 MODEL1909260004 MODEL1703310000 MODEL1909260005 MODEL1909260006 MODEL1311110000 MODEL1311110001

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Pancreas

SUBMITTER: Gereon Poschmann  

LAB HEAD: Gereon Poschmann

PROVIDER: PXD016455 | Pride | 2020-01-24

REPOSITORIES: Pride