Proteomics

Dataset Information

Substrates of human Sec62/Sec63 complex

ABSTRACT: The Sec61-associated Sec62/Sec63 complex supports translocation of only a subset of precursor polypeptides, i.e. in a substrate-specific manner. To characterize Sec62/Sec63-dependent precursors, we combined siRNA-mediated Sec62 or Sec63 depletion in Hela cells or CRISPR/Cas9-mediated knock-down in HEK 293 cells with label-free quantitative proteomics and differential expression analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Richard Zimmermann  

LAB HEAD: Prof. Dr. Richard Zimmermann (lab head)

PROVIDER: PXD012078 | Pride | 2020-03-06

REPOSITORIES: Pride

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20160218_coreQEP1_NaNa_SA_Orbi2155Sample01.raw Raw
20160218_coreQEP1_NaNa_SA_Orbi2155Sample02.raw Raw
20160218_coreQEP1_NaNa_SA_Orbi2155Sample03.raw Raw
20160218_coreQEP1_NaNa_SA_Orbi2155Sample04.raw Raw
20160218_coreQEP1_NaNa_SA_Orbi2155Sample05.raw Raw
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