Dataset Information

RsaC sRNA modulates the oxidative stress response of Staphylococcus aureus during manganese starvation.

ABSTRACT: The human opportunistic pathogen Staphylococcus aureus has developed multiple strategies to adapt to various environments, to fight and escape the immune system, to spread and persist in host tissues. It is responsible for numerous diseases ranging from benign skin infections to more serious such as endocarditis or septicemia. The pathogenicity is due to the production of a multitude of virulence factors, whose synthesis is finely regulated by a combination of regulatory proteins and small non-coding RNAs (sRNAs). Our study reveals an unexpected function of an atypical sRNA, RsaC, which is at the heart of networks controlling defence responses to oxidative stress, manganese import and nutrition immunity. This work highlights a novel mechanism required for S. aureus to survive into its host.

INSTRUMENT(S):

ORGANISM(S): Staphylococcus Aureus

SUBMITTER: Johana Chicher

LAB HEAD: David Lalaouna

PROVIDER: PXD013225 | Pride | 2019-11-11

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	2015_07_A.Tomasini_NewrsaC_WT1-1000ng.mgf	Mgf
	2015_07_A.Tomasini_NewrsaC_WT1-1000ng.wiff	Wiff
	2015_07_A.Tomasini_NewrsaC_WT1-1000ng.wiff.scan	Wiff
	2015_07_A.Tomasini_NewrsaC_WT2-1000ng.mgf	Mgf
	2015_07_A.Tomasini_NewrsaC_WT2-1000ng.wiff	Wiff

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Publications

Nonlinear hydrodynamic theory of crystallization.

Tóth Gyula I GI Gránásy László L Tegze György G

Journal of physics. Condensed matter : an Institute of Physics journal 20131212 5

We present an isothermal fluctuating nonlinear hydrodynamic theory of crystallization in molecular liquids. A dynamic coarse-graining technique is used to derive the velocity field, a phenomenology which allows a direct coupling between the free energy functional of the classical density functional theory and the Navier-Stokes equation. In contrast to the Ginzburg-Landau type amplitude theories, the dynamic response to elastic deformations is described by parameter-free kinetic equations. Employ ...[more]

PMID: 24334547

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