Cross-linking mass spectrometry of the CCAN and CCAN-Cenp-A complexes

ABSTRACT: Here we performed a cross-linking mass spectrometry analysis of the inner kinethocore complex CCAN and of the complex associated with a CenpA-nucleosome (CCAN-CenpA)from budding yeast. These experiments validated the cryo-EM structure of both complexes and provided additional structural insights on the complex organization.

INSTRUMENT(S):

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Domenico Fasci  

LAB HEAD: Albert J.R. Heck

PROVIDER: PXD013769 | Pride | 2019-08-20

REPOSITORIES: Pride