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Proteomic profiling of histone acetylation pattern in Arabidopsis

ABSTRACT: The levels of acetylated and non-acetylated histone peptide forms were quantified in A. thaliana plants with loss of function of HDA6, and plants exposed to HDAs inhibitors (trichostatin and sodium butyrate)during germination .

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

TISSUE(S): Leaf

SUBMITTER: Gabriela Lochmanova

LAB HEAD: Zbynek Zdrahal

PROVIDER: PXD014739 | Pride | 2019-10-14

REPOSITORIES: Pride

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Different Modes of Action of Genetic and Chemical Downregulation of Histone Deacetylases with Respect to Plant Development and Histone Modifications.

Lochmanová Gabriela G Ihnatová Ivana I Kuchaříková Hana H Brabencová Sylva S Zachová Dagmar D Fajkus Jiří J Zdráhal Zbyněk Z Fojtová Miloslava M

International journal of molecular sciences 20191014 20

A high degree of developmental plasticity enables plants to adapt to continuous, often unfavorable and unpredictable changes in their environment. At the molecular level, adaptive advantages for plants are primarily provided by epigenetic machinery including DNA methylation, histone modifications, and the activity of noncoding RNA molecules. Using a mass spectrometry-based proteomic approach, we examined the levels of acetylated histone peptide forms in Arabidopsis plants with a loss of function ...[more]

PMID: 31615119

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