Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: 
Duc Duong
LAB HEAD: Randy A. Hall
PROVIDER: PXD015202 | Pride | 2020-01-13
REPOSITORIES: Pride
Publications
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1.
Nguyen TrangKimberly Thu TT Dammer Eric B EB Owino Sharon A SA Giddens Michelle M MM Madaras Nora S NS Duong Duc M DM Seyfried Nicholas T NT Hall Randy A RA
Journal of proteome research 20200201 2
GPR37 and GPR37L1 are glia-enriched G protein-coupled receptors that have been implicated in several neurological and neurodegenerative diseases. To gain insight into the potential molecular mechanisms by which GPR37 and GPR37L1 regulate cellular physiology, proteomic analyses of whole mouse brain tissue from wild-type (WT) versus GPR37/GPR37L1 double knockout (DKO) mice were performed in order to identify proteins regulated by the absence versus presence of these receptors (data are available v ...[more]
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