Proteomics

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Impact of in ovo administered pioneer colonizers on intestinal proteome of young broiler chickens


ABSTRACT: Pioneer colonization of the gastrointestinal tract by bacteria is thought to have major influence on neonatal tissue development. Previous studies have shown in ovo inoculation of embryos with saline (S), species of Citrobacter (C, C2), or lactic-acid bacteria (LAB) resulted in an altered microbiome on day of hatch (DOH) and by 10 days of age. The current study investigated GIT proteomic changes in relation to different inoculations at DOH and by 10 days of age.

INSTRUMENT(S): Thermo Fisher Scientific instrument model

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Intestinal Mucosa, Epithelial Cell

SUBMITTER: Denise Russi Rodrigues  

LAB HEAD: Lisa Bielke

PROVIDER: PXD015504 | Pride | 2020-01-09

REPOSITORIES: Pride

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Publications

Intestinal Pioneer Colonizers as Drivers of Ileal Microbial Composition and Diversity of Broiler Chickens.

Rodrigues Denise R DR   Winson Emily E   Wilson Kim M KM   Briggs Whitney N WN   Duff Audrey F AF   Chasser Kaylin M KM   Bielke Lisa R LR  

Frontiers in microbiology 20200109


Given that recent advances in metagenomics have highlighted the importance of intestinal microbes for poultry health, there has been a corresponding search for early manipulation strategies of intestinal microbiota in order to advance immune system development and optimize functional properties of growth. In this study, we used the <i>in ovo</i> technique as an experimental model to address how early bacterial intestinal colonization could affect the development and establishment of the mature i  ...[more]

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