Metabolic labeling of NMT substrates by photoactivatable/clickable myristate probes X3/X8/X10

ABSTRACT: Efficiency of labelling by photoactivatable/clickable myristate probes X3/X8/X10 is compared to the positive control probe YnMyr. Additionally, negative controls for each probe were obtained by treatment with NMT ihibitor IMP-366 (DDD85464). The resulting data indicates efficient labeling of NMT substrates by photoactivatable probes that is NMT-dependent.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

SUBMITTER: Roman Fedoryshchak  

LAB HEAD: Edward Tate

PROVIDER: PXD027239 | Pride | 2023-03-11

REPOSITORIES: Pride