S100A4/TCF complex transcription regulation drives epithelial-mesenchymal transition in chronic sinusitis through Wnt/GSK-3β/β-catenin signaling

ABSTRACT: Chronic rhinosinusitis (CRS) is closely associated with remodelling of nasal mucosal tissue during a prolonged inflammatory process, and epithelial mesenchymal transition (EMT) is thought to be involved in this process, but the underlying mechanisms driving this progression are unclear. Using a high-resolution Q Exactive Plus Orbitrap mass spectrometer, we performed a proteomic screen of CRS nasal mucosal tissue to identify differentially expressed proteins.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Nasal Mucosa

SUBMITTER: Ningyue Gong  

LAB HEAD: S100A4/TCF complex transcription regulation drives epithelial-mesenchymal transition in chronic sinusitis through Wnt/GSK-3β/β-catenin signaling

PROVIDER: PXD030884 | Pride | 2022-02-21

REPOSITORIES: Pride