Quantitative Proteomics of Medium-Sized Extracellular Vesicle-Enriched Plasma of Lacunar Infarction for the Discovery of Prognostic Biomarkers
Ontology highlight
ABSTRACT:
INSTRUMENT(S): QSTAR
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Platelet, Blood Plasma
DISEASE(S): Cardiovascular System Disease
SUBMITTER: 
SoFong Cam Ngan
LAB HEAD: Newman Sze
PROVIDER: PXD032225 | Pride | 2023-03-11
REPOSITORIES: Pride
Publications
Quantitative Proteomics of Medium-Sized Extracellular Vesicle-Enriched Plasma of Lacunar Infarction for the Discovery of Prognostic Biomarkers.
Datta Arnab A Chen Christopher C Gao Yong-Gui YG Sze Siu Kwan SK
International journal of molecular sciences 20221001 19
Lacunar infarction (LACI), a subtype of acute ischemic stroke, has poor mid- to long-term prognosis due to recurrent vascular events or incident dementia which is difficult to predict using existing clinical data. Herein, we aim to discover blood-based biomarkers for LACI as a complementary prognostic tool. Convalescent plasma was collected from forty-five patients following a non-disabling LACI along with seventeen matched control subjects. The patients were followed up prospectively for up to ...[more]
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