Quantitative Proteomics of Medium-Sized Extracellular Vesicle-Enriched Plasma of Lacunar Infarction for the Discovery of Prognostic Biomarkers

ABSTRACT: Lacunar infarction (LACI), a difficult to diagnose, subtype of acute ischemic stroke affects around 25% of all ischemic stroke cases. Despite having an excellent recovery during acute phase, certain LACI patients have poor mid- to long-term prognosis due to the recurrence of vascular events or dementia. The existing clinical protocols are unable to predict the prognosis of LACI patients. Blood-based biomarkers maybe useful as complementary prognostic and research tools.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet, Blood Plasma

DISEASE(S): Cardiovascular System Disease

SUBMITTER: SoFong Cam Ngan  

LAB HEAD: Newman Sze

PROVIDER: PXD032225 | Pride | 2023-03-11

REPOSITORIES: Pride