Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Camelidae
TISSUE(S): Blood Serum
SUBMITTER: Lei Fang
LAB HEAD: Lei Fang
PROVIDER: PXD032731 | Pride | 2024-01-26
REPOSITORIES: Pride
Protein science : a publication of the Protein Society 20221101 11
Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused by novel bunyavirus (SFTSV), with a mortality rate of 6.3% ~ 30%. To date, there is no specific treatment for SFTS. Previously, we demonstrated that SFTSV surface glycoprotein (Glycoprotein N, Gn) was a potential target for the development of SFTS vaccine or therapeutic antibodies, and anti-Gn neutralizing antibodies played a protective role in SFTS infection. Compared with traditional antibodies, nanobodies ...[more]