Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Toxoplasma Gondii Rh
DISEASE(S): Toxoplasmosis
SUBMITTER: Ignasi Forne
LAB HEAD: Prof. Dr. rer. nat. Markus Meissner
PROVIDER: PXD035654 | Pride | 2023-01-30
REPOSITORIES: Pride
Singer Mirko M Simon Kathrin K Forné Ignasi I Meissner Markus M
PLoS biology 20230105 1
Apicomplexa are obligate intracellular parasites. While most species are restricted to specific hosts and cell types, Toxoplasma gondii can invade every nucleated cell derived from warm-blooded animals. This broad host range suggests that this parasite can recognize multiple host cell ligands or structures, leading to the activation of a central protein complex, which should be conserved in all apicomplexans. During invasion, the unique secretory organelles (micronemes and rhoptries) are sequent ...[more]