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Glc and 1-NM-PP1 timecourses in tpk1/2/3as; TMT2 (4646)

ABSTRACT: Samples taken at different timepoints after glucose addition. Strain ACY142. Different timepoints after 1-NM-PP1; for model building

INSTRUMENT(S):

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Michael Plank

LAB HEAD: Andrew Capaldi

PROVIDER: PXD036029 | Pride | 2024-06-16

REPOSITORIES: Pride

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			Action	DRS
	20220517_C3P0_4666_Aa.raw	Raw
	20220517_C3P0_4666_Ab.raw	Raw
	20220517_C3P0_4666_Ac.raw	Raw
	20220517_C3P0_4666_Ba.raw	Raw
	20220517_C3P0_4666_Bb.raw	Raw

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Publications

Systems level analysis of time and stimuli specific signaling through PKA.

Plank Michael M Carmiol Nicole N Mitri Bassam B Lipinski Austin A AA Langlais Paul R PR Capaldi Andrew P AP

Molecular biology of the cell 20240306 4

It is well known that eukaryotic cells create gradients of cAMP across space and time to regulate the cAMP dependent protein kinase (PKA) and, in turn, growth and metabolism. However, it is unclear how PKA responds to different concentrations of cAMP. Here, to address this question, we examine PKA signaling in <i>Saccharomyces cerevisiae</i> in different conditions, timepoints, and concentrations of the chemical inhibitor 1-NM-PP1, using phosphoproteomics. These experiments show that there are n ...[more]

PMID: 38446618

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