Mosquito salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission

ABSTRACT: To identify the putative salivary tPA activator, we fractionated salivary proteins by size-exclusion chromatography and identified fraction Z8 as the strongest tPA activator, whereas the adjacent fractions Z7 and Z9 activated tPA at lower levels. Mass spectrometry analysis of these fractions identified a total of 152 unique proteins.

INSTRUMENT(S):

ORGANISM(S): Anopheles Gambiae (african Malaria Mosquito)

TISSUE(S): Salivary Gland

SUBMITTER: Motoshi Suzuki  

LAB HEAD: Joel Vega-Rodriguez

PROVIDER: PXD052155 | Pride | 2025-01-16

REPOSITORIES: Pride