Dataset Information

BME/CTVM6 cells infected by SFTSV MOI 1

ABSTRACT: Study of tick cells from the Rhipicephalus microplus vector (BME/CTVM6) were infceted by SFTS virus at MOI of 1 PFU/cell. We collected samples at day 3 and 6 post-infection, and added the mock infected control. This was done in 4 replicates, and allow us to perform a proteomics informed by transcriptomic study, as well as differentially protein expression analysis.

INSTRUMENT(S):

ORGANISM(S): Rhipicephalus Microplus

TISSUE(S): Embryonic Cell

SUBMITTER: Marine Petit

LAB HEAD: Marine J. Petit

PROVIDER: PXD054068 | Pride | 2025-05-26

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	163_282_2022_MP_orfseq_SFTSV_directDIA_ConditionSetup.tsv	Tabular
	163_282_2022_MP_orfseq_SFTSV_directDIA_Report_Protein_pivot_FP.xls	Xls
	163_282_2022_MP_orfseq_SFTSV_directDIA_Report_peptide_pivot_FP.xls	Xls
	164_2022-MP-D3-1.raw	Raw
	164_2022-MP-D3-2.raw	Raw

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Publications

Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors.

Petit Marine J MJ Flory Charlotte C Gu Quan Q Fares Mazigh M Lamont Douglas D Score Alan A Davies Kelsey K Bell-Sakyi Lesley L Scaturro Pietro P Brennan Benjamin B Kohl Alain A

Nature communications 20250521 1

The increasing prevalence of tick-borne arboviral infections worldwide necessitates advanced control strategies, particularly those targeting vectors, to mitigate the disease burden. However, the cellular interactions between arboviruses and ticks, especially for negative-strand RNA viruses, remain largely unexplored. Here, we employ a proteomics informed by transcriptomics approach to elucidate the cellular response of the Rhipicephalus microplus-derived BME/CTVM6 cell line to severe fever with ...[more]

PMID: 40399277

Dataset Information

BME/CTVM6 cells infected by SFTSV MOI 1

Dataset's files

Publications

Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors.

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