Dataset Information
LncRNA LINC00622 directly bingding proteins in melanoma cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Melanocyte, Skin
DISEASE(S): Skin Melanoma
SUBMITTER: 
can li
LAB HEAD: can Li
PROVIDER: PXD055040 | Pride | 2025-07-21
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| checksum.txt | Txt | |||
| codex.xls | Xls | |||
| database_search_result.zip | Other | |||
| original_data.zip | Other |
Items per page: 1 - 4 of 4 |
Publications
LINC00622 transcriptionally promotes RRAGD to repress mTORC1-modulated autophagic cell death by associating with BTF3 in cutaneous melanoma.
Cell death & disease 20250712 1
Autophagy plays critical and complicated roles in tumors. As the central hub of nutrient signaling and cell growth, mTOR constitutes mTORC1 to be the main gateway for modulating autophagy. Yet, the regulatory mechanisms of mTORC1-regulated autophagy in tumors are not fully deciphered. Here, we report a novel long noncoding RNA, LINC00622, which modulates mTORC1-regulated autophagy in cutaneous melanoma. Functionally, LINC00622 acts as a pro-oncogenic factor to promote proliferation, colony forma ...[more]
