Proteomics

Dataset Information

0

Ornithodoros Lahorensis Salivary gland LC-MSMS

ABSTRACT: Ticks are hematophagous vectors of great medical and veterinary importance because they transmit numerous pathogenic microorganisms to humans and animals. The argasid Ornithodoros lahorensis is the vector of tickborne Anaplasma ovis,Crimean-Congo haemorrhagic fever virus and other pathogenic. Tick salivary gland express bioactive molecules that perform key functions in blood feeding and pathogen transmission. To explore new strategies for tick control, in this work we have obtained and compared the salivary gland proteomics of O.lahorensis before and after a blood meal and identified the DEPs regulated after feeding. The proteins were annotated, functionally and their expression levels compared between both physiological conditions (unfed females/males and fed females/males at 24h post-engorgement).

INSTRUMENT(S):

ORGANISM(S): Ornithodoros Sp. Ajm-2011b

TISSUE(S): Salivary Gland

SUBMITTER: Yuan Xiangfen  

LAB HEAD: Xiangfen Yuan

PROVIDER: PXD059319 | Pride | 2025-12-08

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
Ornithodoros_lahorensis.fa Other
Ornithodoros_lahorensis.ko Other
Ornithodoros_lahorensis.path Other
Ornithodoros_lahorensis.protein2KEGG.xls Xls
Ornithodoros_lahorensis.protein2kog.xls Xls
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Publications

Quantitative proteomic analysis of salivary glands in female Ornithodoros lahorensis (syn. Alveonasus lahorensis) after blood feeding via DIA-coupled LC-MS/MS.

Yuan Xiangfen X   Xu Xiaolin X   Wang Huiyu H   Jing Hongli H   Qiu Songyin S   Kong Yufang Y   Zhang Yue Y   Lv Jizhou J   Suo Xun X   Wu Shaoqiang S  

Ticks and tick-borne diseases 20251201 6

Ornithodoros lahorensis (syn. Alveonasus lahorensis) is a species of soft tick within the Argasidae family, known for causing debilitating symptoms, as well as transmitting pathogens that pose significant health risks and economic losses to affected livestock and potentially humans. The salivary gland is the key component in the pathogenic mechanisms of ticks, as it not only facilitates feeding but also serves as a medium for pathogen transmission. Here, data-independent acquisition (DIA) couple  ...[more]

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