Whole Cell and Ubiquitinated Proteome of the Endoplasmic Reticulum (ER) Stress Response to Mild Hypothermic Culture Conditions in Chinese Hamsters Ovary Cells

ABSTRACT: This study investigates the impact of mild hypothermic conditions (31°C) on the whole cell proteome and ubiquitinated proteome of Chinese hamster ovary (CHO) cells, with a specific focus on endoplasmic reticulum (ER) proteins and ER stress. Using high-resolution mass spectrometry, we conducted a comprehensive proteomic and ubiquitinated proteomic analysis to quantify changes in protein abundance and ubiquitinated peptides under mild hypothermia.

INSTRUMENT(S):

ORGANISM(S): Cricetulus Griseus (chinese Hamster) (cricetulus Barabensis Griseus)

TISSUE(S): Cell Culture

SUBMITTER: David Ryan  

LAB HEAD: Paula Meleady

PROVIDER: PXD063085 | Pride | 2025-12-22

REPOSITORIES: Pride