The Human Lens Fiber Cytoskeletome Reveals Neuronal Signatures, and the presence of Chaperonins, Signaling, Proteasome and Redox Regulators

ABSTRACT: Morphogenesis, growth, shape, mechanics, and transparency of the ocular lens critically depend on cytoskeletal networks and cell adhesive interactions. However, the molecular composition of these cellular components of lens fibers remains to be defined in depth. This study is aimed at providing an unbiased and comprehensive characterization of cytoskeletal and cytoskeleton-associated proteins in human lens fibers.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain, Fibroblast

DISEASE(S): Disease Free

SUBMITTER: Nik Skiba  

LAB HEAD: Ponugoti V. Rao

PROVIDER: PXD069327 | Pride | 2026-05-25

REPOSITORIES: Pride