Proteomics

Dataset Information

0

Identification of ECE1-interacting proteins


ABSTRACT: LN229 cells were subjected to Co-IP using IgG and anti-ECE1 antibodies. The immunoprecipitated complexes were validated by Western blot and subsequently analyzed by liquid chromatography–mass spectrometry (HPLC-MS/MS, QLBio, China) for identification of ECE1-interacting proteins.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Liangliang wang  

LAB HEAD: Xingang Li

PROVIDER: PXD071913 | Pride | 2026-04-27

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
HFX1_LFQ_X0006250418_ECE1.raw Raw
HFX1_LFQ_X0006250418_IgG_M.raw Raw
HFX1_LFQ_X0006250418_IgG_R.raw Raw
HFX1_LFQ_X0006250418_MSMSSpectrumInfo.txt Txt
HFX1_LFQ_X0006250418_PSMs.txt Txt
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Publications

ECE1c promotes glioblastoma invasion via the ROCK2-MYH10 axis and interaction with ACTB.

Wang Liangliang L   Zhao Feihu F   Sun Yanfei Y   Liu Jilong J   Wang Jiazheng J   Wang Jian J   Huang Bin B   Li Xingang X  

American journal of translational research 20260315 3


<h4>Background</h4>Glioblastoma is the most malignant primary intracranial tumor and is characterized by rapid growth, diffuse invasion, and notable therapeutic resistance. The mesenchymal subtype of glioblastoma multiforme (GBM) is the most aggressive, but the underlying regulatory network of this phenotype has not yet been fully elucidated.<h4>Methods</h4>Bioinformatic analysis was performed to identify the heterogeneity of ECE1 expression and its prognostic roles. Cytological experiments were  ...[more]

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