Glycopeptide analysis of A549 cells after influenza A infection

ABSTRACT: Influenza A virus (IAV) hijacks host cellular machinery, but many virus–IAV interactions and contacting protein sites remain uncharacterised, particularly those dependent on intact cellular architecture, such as membrane-associated or phase-separated compartments. Here, we applied in-cell cross-linking mass spectrometry (XL-MS), integrated with AlphaFold-based structural modelling and functional assays, to map protein-protein contact sites in IAV-infected human cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Influenza A Virus (a/india/p063078/2006(h3n2))

SUBMITTER: Frank Stein  

LAB HEAD: Jan Kosinski

PROVIDER: PXD072851 | Pride | 2026-04-23

REPOSITORIES: Pride