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MassProteomic Analysis of MIRO2 Interacting Proteins by Co-IP and Mass Spectrometry

ABSTRACT: This project investigates the interactome of MIRO2 using co-immunoprecipitation (Co-IP) followed by mass spectrometry analysis. Control and MIRO2-FLAG overexpressing cells were subjected to Co-IP to identify proteins that interact with MIRO2 and potentially facilitate mitochondrial-derived vesicle (MDV) trafficking to lysosomes under hypoxia/reoxygenation (H/R) stress. The dataset provides insights into MIRO2-associated protein complexes and their roles in lysosomal renewal, MDV formation, and organelle quality control.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Zhuofan Li

LAB HEAD: Zhiyin Song

PROVIDER: PXD078488 | Pride | 2026-06-03

REPOSITORIES: Pride

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			Action	DRS
	Control-cell-1.raw	Raw
	Control-cell-2.raw	Raw
	Control-cell-3.raw	Raw
	MIRO2-FLGAG-IP-search.xlsx	Xlsx
	MIRO2-Flag-cell-1.raw	Raw

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