Project description:Mycobacterium tuberculosis is a pathogenic bacterium that was sequenced and annotated as early as 1998, but in recent years it has been found that its annotation is not complete. Therefore, we used a proteogenomics strategy to re-annotate Mycobacterium tuberculosis H37Rv, identifying 37 'new genes' and correcting 35 existing gene models.
Project description:THP-1 Macrophages were infected with Mycobacterium tuberculosis clinical isolates from Xinjiang, China, and H37Rv for 24 hours, respectively, and their transcriptomes were sequenced to investigate the specific biological processes that occur after infection of macrophages with Mycobacterium tuberculosis clinical isolates from Xinjiang, China.
Project description:Transcriptional profiling of mycobacterium tuberculosis clinical isolates in China comparing extensively drug-resistant tuberculosis with drug sensitive one.
