Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Analysis of gene expression profiles of Hikeshi knockout MEF cells.

PROVIDER: PRJDB5823 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR093597.fastq.gz	Fastqsanger.gz
	DRR093598.fastq.gz	Fastqsanger.gz
	DRR093599.fastq.gz	Fastqsanger.gz
	DRR093600.fastq.gz	Fastqsanger.gz
	DRR093601.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 20

Similar Datasets

Mus musculus

Project description:Gene expression array assay of Lsh WT and Knockout MEF cells

| PRJNA142993 | ENA

Mus musculus

Project description:Expression data from Dicer knockout MEF

| PRJNA97783 | ENA

Mus musculus

Project description:CTCF binding profiles in MEF cells

| PRJNA286789 | ENA

Mus musculus

Project description:Comparison of gene expression profiles in diploid and transformed tetraploid MEF cells

| PRJNA123855 | ENA

Bidirectional Introgression between Mus musculus domesticus and Mus spretus.

Project description:Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion of introgression decreased with geographic distance from the area of sympatry. Introgression was observed on all autosomes for both species, but not on the X-chromosome in M. m. domesticus, consistent with known X-linked hybrid sterility and inviability genes that have been mapped to the M. spretus X-chromosome. Tract lengths were generally short with a few outliers of up to 2.7 Mb. Interestingly, the longest introgressed tracts were in olfactory receptor regions, and introgressed tracts were significantly enriched for olfactory receptor genes in both species, suggesting that introgression may be a source of functional novelty even between species with high barriers to gene flow.

| S-EPMC8784167 | biostudies-literature

Mus musculus

Project description:Compare gene expression profiles of mouse iNSC, WT-NSC, and MEF

| PRJNA164693 | ENA

RNA-Seq JunB WT and KO Tregs Mus musculus

Project description:To understand the mechanisms through which JunB regulates Tregs-mediated immune regulation, we examined the global gene expression profiles in the JunB WT and KO Tregs by performing RNA sequencing (RNA-seq) analysis.

2019-05-07 | GSE129060 | GEO

Characterization of nucleolus-associated domains in mus musculus and their dynamics after inactivation of the Upstream binding factor protein

Project description:Nucleolus-associated DNA was isolated from MEF cells before and after conditional knock-out of UBF and hybridized against genomic DNA in biological replicates. Two different types of immortalized MEF cells were used. MEFs were immortalized by genetic depletion of p53, iMEFs were immortalized by transfection of the SV40 Tt antigen.

2018-02-02 | GSE80441 | GEO

Mus musculus

Project description:Gene expression profiles of p63 knockout mouse

| PRJNA275329 | ENA

Mus musculus

Project description:Comparison of the gene expression profiles between MEF, MEF treated with n-Butylenephthalide (BP) 10 and 40ug/ml.

| PRJNA153027 | ENA