Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Molecular characterization and phylogenetic analysis of fungi and bacteria producing bioactive substances.

ABSTRACT: Molecular and phylogenetic investigations of different fungi and bacteria producing bioactive substances for their possible use as biocontrol agents against different agriculturally important phytopathogens.

PROVIDER: PRJEB43921 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Bioactive RNA in Maternal Breastmilk

Project description:Bioactive RNA in Maternal Breastmilk

| PRJNA791909 | ENA

Bioactive genes in Spirulina

Project description:Identification of bioactive genes from cyanobacteria, Arthrospira platensis

| PRJEB24977 | ENA

Random bioactive sequences

Project description:Random sequences are an abundant source of bioactive RNAs or peptides

| PRJEB19640 | ENA

Responses of various cells in the zebrafish olfactory epithelium after treatment with alarm substances

Project description:We performed single-cell transcriptome sequencing of the olfactory epithelium of AB strain zebrafish. We also applied alarm substances to one of the groups and studied the response of the olfactory epithelium to alarm substances by comparing the proportions of various cell types and transcriptional changes between the experimental and control groups.

2025-12-09 | GSE283486 | GEO

umami experiment-Analysis of the effect of amino-acids and humic substances on the transcriptome of Arabidopsis

Project description:2022_13_qs_umami- umami experiment-Analysis of the effects of biostimulants (amino-acids and humic substances) on plants-Analysis of transcriptomic variations in Arabidopsis seedlings grown in vitro with or without humic substances or amino acid solutions.

2025-10-22 | GSE297649 | GEO

COSMIC-seq of bioactive N-methylpyrrole/N-methylimidazole polyamides

Project description:Targeting the genome with sequence-specific DNA-binding molecules is a major goal at the interface of chemistry, biology, and precision medicine. Polyamides, composed of N-methylpyrrole and N-methylimidazole monomers, are a class of synthetic molecules that can be rationally designed to “read” specific DNA sequences. However, the impact of different chromatin states on polyamide binding to its cognate sites across the genome is a crucial parameter that remains unresolved. We applied COSMIC-seq (crosslinking of small molecules to isolate chromatin) to directly map, for the first time, the genome-wide binding profiles of two bioactive and structurally distinct polyamides in cells.

2016-11-08 | GSE70267 | GEO

Bioactive Compounds from Endophytic fungus Curvularia sorghina

Project description:Bioactive Compounds from Endophytic fungus Curvularia sorghina

| PRJEB25627 | ENA

Bioactive peptides from Channa striatus

Project description:Exploration of bioactive peptides from innate immune molecules of Channa striatus

| PRJEB25012 | ENA

Screening bioactive food compounds in honey bees suggests curcumin blocks alcohol-induced damage to longevity and DNA methylation

Project description:Various bioactive food compounds may confer health and longevity benefits, possibly through altering or preserving the human epigenome. While bioactive food compounds are widely being marketed as ‘improving health and longevity’ by counteracting harmful effects of poor nutrition and lifestyle, claimed effects are often not adequately documented. Using the honey bee (Apis mellifera) as a model species, we here employed a multi-step screening approach to investigate seven compounds for effects on lifespan and DNA methylation using ELISA and whole genome bisulfite sequencing (WGBS). A positive longevity effect was detected for valproic acid, isovaleric acid, and cyanocobalamin. For curcumin, we found that lifespan shortening caused by ethanol intake, was restored when curcumin and ethanol were co-administered. Furthermore, we identified region specific DNA methylation changes as a result of ethanol intake. Ethanol specific changes in DNA methylation were fully or partially blocked in honey bees receiving ethanol and curcumin together. Ethanol-affected and curcumin-blocked differentially methylated regions covered genes involved in fertility, temperature regulation and tubulin transport. Our results demonstrate fundamental negative effects of low dose ethanol consumption on lifespan and associated DNA methylation changes and present a proof-of-principle on how longevity and DNA methylation changes can be negated by the bioactive food component curcumin. Our findings provide a fundament for further studies of curcumin in mice and humans and offer an avenue to explore regarding possible prevention of health issues related to alcohol consumption.

2021-09-27 | GSE169362 | GEO

p21 produces a bioactive secretome that places stressed cells under immuno-surveillance [dataset 10]

Project description:p21 produces a bioactive secretome that places stressed cells under immuno-surveillance

2021-10-29 | GSE169326 | GEO