Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of non-lesional and lesional human skin of positive patch-test reactions to nickel at 24h, 48h, and 120h post allergen application

ABSTRACT: Transcriptional profiling of non-lesional and lesional human skin of positive patch-test reactions to nickel at 24h, 48h, and 120h post allergen application

PROVIDER: PRJEB56467 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR10307600.fastq.gz	Fastqsanger.gz
	ERR10307601.fastq.gz	Fastqsanger.gz
	ERR10307602.fastq.gz	Fastqsanger.gz
	ERR10307603.fastq.gz	Fastqsanger.gz
	ERR10307604.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Transcriptional profiling of non-lesional and lesional human skin of positive patch-test reactions to nickel at 24h, 48h, and 120h post allergen application

Project description:Donor-matched human skin biopsies were taken from non-lesional (NL) and lesional skin of positive patch-test reactions to nickel at 24h, 48h, and 120h post allergen application, respectively, and bulk RNA-seq was performed.

2022-10-31 | E-MTAB-12237 | biostudies-arrayexpress

Transcriptomic analysis of severe allergic patch test reactions to different allergens (nickel, 2-hydroxyethylmethacrylate, methylisothiazolinone and formaldehyde)

Project description:Background: Immune mechanisms underlying elicitation in allergic contact dermatitis (ACD) are not disclosed. Previous studies have shown a double-faceted nature of ACD with both common biomarkers between different allergens, as well as allergen-specific imprinting, with discordance in terms of relevant involved immune pathways. Objectives: To characterize molecular signatures and their immune mechanisms between different relevant allergens (nickel, 2-hydroxyethylmethacrylate (2-HEMA), methylisothiazolinone (MI), formaldehyde) in strong and extreme patch test reactions of patients without atopic dermatitis using RNA sequencing.

2025-07-16 | GSE282562 | GEO

Transcriptomic analysis of severe allergic patch test reactions to different allergens (nickel, 2-hydroxyethylmethacrylate, methylisothiazolinone and formaldehyde)

Project description:Transcriptomic analysis of severe allergic patch test reactions to different allergens (nickel, 2-hydroxyethylmethacrylate, methylisothiazolinone and formaldehyde)

| PRJNA1189143 | ENA

Microarray data vitiligo patients lesional and non-lesional skin

Project description:lesional and non-lesional skin from vitiligo patients

2016-11-01 | GSE75819 | GEO

Gene expression profile of nickel-stimulated HUVEC

Project description:Nickel compounds, important carcinogens and prime inducers of contact allergy in humans, are potent activators of endothelial cells (ECs). To elucidate the signaling pathways mediating the cellular responses to nickel we performed Affymetrix gene profiling of human primary ECs. Keywords: stress response

2006-12-31 | GSE4852 | GEO

Gene expression profiling in psoriatic lesional and non-lesional skin [brodalumab treatment]

Project description:To explore the psoriasis phenotype and pathways involved in psoriasis, we characterized gene expression in lesional and non-lesional skin from psoriasis patients. Furthermore, we explored the effects of various doses of brodalumab on lesional skin over time. From each of the 25 psoriasis patients, we obtained two pre-dose biopsies, one from a lesion and the other from non-lesional skin in the same general body geography, and two post-dose biopsies. Total RNA was extracted from 6mm punch biopsies that were split in half. A total of 99 samples were run on Affymetrix HU133 Plus 2.0 microarrays. There was no paired non-lesional sample for 'T_lesional_pre-dose' (skn55789).

2014-03-31 | E-GEOD-53552 | biostudies-arrayexpress

Nickel Chloride (NiCl2) effect on human T cells from whole blood

Project description:Analysis of anti-CD3/anti-CD28 stimulated T cells treated with or without nickel chloride. Nickel is the most important contact allergen in the general population of the industrialized world. Results provide insight into the biological effects of nickel on human CD3+ T cells.

2011-05-18 | GSE23387 | GEO

Gene expression profiling in psoriatic lesional and non-lesional skin [brodalumab treatment]

2014-03-31 | GSE53552 | GEO

Transcriptomic analysis of the nickel response in roots and shoots in the nickel hyperaccumulator Leucocroton havanensis (Euphorbiaceae) endemic from Cuba.

Project description:The goal of this study was to produce a reference transcriptome for the nickel hyperaccumulator Leucocroton havanensis endemic from Cuba and use this transcriptome as a reference to identify genes responding to the presence or the absence of nickel in both roots and shoots of this species

2024-07-10 | GSE237255 | GEO

Gene expression profiling in psoriatic lesional and non-lesional skin [Set 1]

Project description:To explore the psoriasis phenotype, we characterize gene expression in lesional and non-lesional skin from psoriasis patients.

2013-01-28 | GSE34248 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data